7.3.1 Headache attributed to neurosarcoidosis

Description:
Headache caused by neurosarcoidosis, associated with aseptic meningitis, cranial nerve lesions, intracranial space-occupying lesion(s) on brain MRI, periventricular inflammatory focal lesions and/or homogeneously enhancing mass lesions on brain or spinal MRI that are confirmed on biopsy as non-caseating granulomas.

Diagnostic criteria:
A. Any headache fulfilling criterion C
B. Neurosarcoidosis has been diagnosed
C. Evidence of causation demonstrated by at least two of the following:

    1. headache has developed in temporal relation to the onset of neurosarcoidosis
    2. either or both of the following:

      a) headache has significantly worsened in parallel with worsening of neurosarcoidosis
      b) headache has significantly improved in parallel with improvement in neurosarcoidosis

    3. headache is accompanied by one or more cranial nerve palsies

D. Not better accounted for by another ICHD-3 diagnosis.

Comment:
Other manifestations of neurosarcoidosis include aseptic meningitis, cranial nerve lesions, intracranial space-occupying lesion(s) on brain MRI, periventricular inflammatory focal lesions and/or homogeneously enhancing mass lesions on brain or spinal MRI that are confirmed on biopsy as non-caseating granulomas.