6.8 Headache attributed to genetic vasculopathy

Headache occurring as part of the phenotypic spectrum of the genetic cerebral vasculopathies, mostly manifesting as recurrent attacks of headache, which may have the features of migraine with or without aura. Attacks can recur for years, and are usually associated from onset, or after a variable delay, with other manifestations of the causative mutation.

Diagnostic criteria:
A. Recurrent attacks of headache fulfilling criterion C
B. A genetic vasculopathy has been diagnosed by appropriate genetic testing
C. Headache is either:

    1. migraine-like
    2. the presenting symptom of stroke-like episodes

D. Not better accounted for by another ICHD-3 diagnosis.